Naringenin

Naringenin

SCHEMBL20571

O=C1CC(c2ccc(O)cc2)Oc2cc(O)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 1.00
CYP3A4 P08684 5/20 1.00
CYP1A1 P04798 4/20 1.00
CYP1A2 P05177 4/20 1.00
CYP1B1 Q16678 4/20 1.00
TTR P02766 4/20 1.00
CYP2C19 P33261 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP2C9 P11712 2/20 1.00
CA12 O43570 2/20 1.00
SLCO2B1 O94956 2/20 1.00
CA4 P22748 2/20 1.00
PSMB5 P28074 2/20 1.00
CA7 P43166 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
ALOX12 P18054 1/20 1.00
ESR1 P03372 1/20 1.00
SHBG P04278 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naringenin SCHEMBL20570 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL25894738 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL1048136 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL17166263 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL29351357 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30785808 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30377739 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30267460 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL3814677 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30785807 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20593 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP claimed
EP-4747367-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES Symrise AG (DE) 2026-05-27 EP claimed
EP-4748368-A1 COMPOSITION FOR ORAL HYGIENE PRODUCTS COMPRISING N-CETYLPYRIDINIUM CHLORIDE, A FLAVONOID AND A POLYMER Curaden AG (CH) 2026-05-27 EP claimed
EP-4749288-A1 COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM COSA Group GmbH (DE) 2026-05-27 EP claimed
CN-122082269-A Wool fiber, dyeing method thereof, ionic liquid and preparation method thereof 2026-05-26 CN claimed
CN-121221800-B Multifunctional supermolecule nano platform and application thereof TIANJIN FIRST CENTER HOSPITAL (CN) 2026-05-26 CN claimed
CN-122074540-A Rosemary serving as preservative and extraction process thereof 2026-05-26 CN claimed
CN-122081102-A Microbial strain for de novo synthesis of gardenia flavin B and application of microbial strain in production of polymethoxy flavonoid compound 2026-05-26 CN claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
CN-122056867-A Citrus flavonoid compound and application thereof in treating acute lung injury 华中农业大学 2026-05-19 CN claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
EP-0242892-A1 Process for activating rhizobium nodulation promoters Rijksuniversiteit Leiden (NL) 1987-10-28 EP claimed
EP-0223245-A2 Curable compositions for dental drugs having sustained release property MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-27 EP claimed
EP-0206219-A1 Photostabilising of sydnonimines CASSELLA Aktiengesellschaft (DE) 1986-12-30 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed
EP-0067913-B1 COMPOSITION FOR THE TREATMENT OF ACNE RUSH-HAMPTON INDUSTRIES, INC. (US) 1984-12-05 EP claimed
EP-0067913-A1 Composition for the treatment of acne RUSH-HAMPTON INDUSTRIES, INC. (US) 1982-12-29 EP claimed
US-4334020-A Method of producing L-glutamic acid by fermentation AJINOMOTO COMPANY INCORPORATED (JP) 1982-06-08 US claimed
US-4297348-A USING NARINGIN, NARINGENIN AND PARTIALLY HYDROLYZED NARINGIN RUSH-HAMPTON INDUSTRIES, INC. (US) 1981-10-27 US claimed
US-4105675-A REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT THE COCA-COLA COMPANY (US) 1978-08-08 US claimed