Naringenin

Naringenin

SCHEMBL17166263

O=C1C[C@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 1.00
CYP3A4 P08684 5/20 1.00
CYP1A1 P04798 4/20 1.00
CYP1A2 P05177 4/20 1.00
CYP1B1 Q16678 4/20 1.00
TTR P02766 4/20 1.00
CYP2C19 P33261 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP2C9 P11712 2/20 1.00
CA12 O43570 2/20 1.00
SLCO2B1 O94956 2/20 1.00
CA4 P22748 2/20 1.00
PSMB5 P28074 2/20 1.00
CA7 P43166 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
ALOX12 P18054 1/20 1.00
ESR1 P03372 1/20 1.00
SHBG P04278 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naringenin SCHEMBL20570 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL25894738 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL20571 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL1048136 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL29351357 1.00 CYP19A1 (1.00) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30785808 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30377739 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30267460 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL3814677 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1
Naringenin SCHEMBL30785807 0.99 CYP19A1 (0.97) CYP19A1CYP3A4CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN claimed
CN-114230541-A Manual naringenin splitting method and absolute configuration determining method 浙江省柑橘研究所 2022-03-25 CN claimed
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers FIRMENICH SA (CH) 2026-05-26 US disclosed
WO-2025215165-A1 LIQUID ANTIMICROBIAL COMPOSITION MINASOLVE SAS (FR) 2025-10-16 WO disclosed
CN-119587671-A Traditional Chinese medicine composition for treating digestive tract polyp and digestive tract tumor as well as preparation and application thereof 中国中医科学院望京医院(中国中医科学院骨伤科研究所) 2025-03-11 CN disclosed
WO-2025043394-A1 KIT FOR FORMING SUPRAMOLECULAR SELF-ASSEMBLY COMPLEX AND USE THEREOF 北京睿创康泰医药研究院有限公司 2025-03-06 WO disclosed
CN-114364265-B Flavanone derivatives and their use as sweetness enhancers 弗门尼舍有限公司 2025-01-03 CN disclosed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US disclosed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US disclosed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US disclosed
US-20230136465-A1 PLANT-BASED CHICKEN FLAVORING AGENT COMPOSITION NotCo Delaware AI, LLC 2023-05-04 US disclosed
CN-114364265-A Flavanone derivatives and their use as sweetness enhancers 弗门尼舍有限公司 2022-04-15 CN disclosed
CN-114230541-A Manual naringenin splitting method and absolute configuration determining method 浙江省柑橘研究所 2022-03-25 CN disclosed
CN-114230541-A Manual naringenin splitting method and absolute configuration determining method 浙江省柑橘研究所 2022-03-25 CN disclosed
US-20220025267-A1 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN ACQUISITION SUB, INC. 2022-01-27 US disclosed
US-20220025267-A1 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN ACQUISITION SUB, INC. 2022-01-27 US disclosed
WO-2020159620-A9 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN INC. (US) 2020-10-22 WO disclosed
CN-108967756-A It is a kind of can help but also defaecation drinks 郑州国手生物科技有限公司 2018-12-11 CN disclosed
CN-108271959-A The super drinks made of tomato, hawthorn, jujube, mulberry fruit 郑州国手生物科技有限公司 2018-07-13 CN disclosed
US-9155792-B2 RecA inhibitors with antibiotic activity, compositions and methods of use TRUSTEES OF BOSTON UNIVERSITY (US) 2015-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers TAS2R10, TAS2R20, TAS2R7 CYP19A1 2593/4885CYP3A4 3109/4885CYP1A1 3286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.