Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20575206 | 0.93 | ITGB3 (0.45) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20575025 | 0.93 | MEN1 (0.41) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20575605 | 0.92 | MEN1 (0.42) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20574581 | 0.87 | ITGB3 (0.39) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20575617 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20574574 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL2833888 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20574516 | 0.84 | KMT2A (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2841846 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL20575166 | 0.81 | MAPK1 (0.45) | ITGB3ITGA2BITGAVITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180344803-A1 | Methods and Compositions For the Treatment of Proteinuric Diseases | THE GENERAL HOSPITAL CORPORATION | 2018-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180344803-A1 | Methods and Compositions For the Treatment of Proteinuric Diseases | ITGB3, PLAUR, PROC | ITGB3 1/4885ITGA2B 4/4885ITGAV 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.