Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 19/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 17/20 | 1.00 |
| ▸ | NCOR2 | Q9Y618 | 16/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 15/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577384 | 1.00 | HDAC3 (1.00) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL20577365 | 0.90 | HDAC3 (1.00) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL20577362 | 0.90 | HDAC3 (1.00) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL23992177 | 0.76 | HDAC1 (0.62) | HDAC3HDAC1NCOR2HDAC2NCOR1 | |
| SCHEMBL32662656 | 0.75 | HDAC1 (0.63) | HDAC3HDAC1NCOR2HDAC2NCOR1 | |
| SCHEMBL20577366 | 0.75 | HDAC1 (0.79) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL20577367 | 0.75 | HDAC1 (0.79) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL23745937 | 0.74 | HDAC3 (0.60) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL30416052 | 0.73 | HDAC1 (0.68) | HDAC3HDAC1NCOR2HDAC2HDAC8 | |
| SCHEMBL32662752 | 0.72 | HDAC1 (0.59) | HDAC3HDAC1NCOR2HDAC2NCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018223122-A1 | HDAC3-SELECTIVE INHIBITORS | OHIO STATE INNOVATION FOUNDATION (US) | 2018-12-06 | — | — | WO | disclosed |