SCHEMBL20577752

SCHEMBL20577752

CC=CC(=O)Oc1ccc2cc(OC(=O)C=CC)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.51
KMT2A Q03164 7/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
NCEH1 Q6PIU2 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
KDM4E B2RXH2 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
MAOB P27338 1/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14989046 0.93 KMT2A (0.54) CA2KMT2AMEN1MAPTTDP1
SCHEMBL14989047 0.93 KMT2A (0.54) CA2KMT2AMEN1MAPTTDP1
SCHEMBL9818747 0.81 CA2 (0.44) CA2KMT2AMAPTKDM4EALDH1A1
SCHEMBL9818749 0.81 CA2 (0.44) CA2KMT2AMAPTKDM4EALDH1A1
SCHEMBL20577757 0.81 HSD17B10 (0.46) CA2KMT2AMEN1MAPTLMNA
SCHEMBL8613434 0.81 KMT2A (0.50) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL8613432 0.81 KMT2A (0.50) KMT2AMEN1MAPTTDP1KDM4E
SCHEMBL8368509 0.81 CA12 (0.68) CA2KMT2AMEN1TDP1KDM4E
SCHEMBL19333584 0.79 KMT2A (0.47) KMT2AMEN1MAPTNCEH1TDP1
SCHEMBL5176450 0.79 ELANE (0.46) CA2KMT2AMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920000-B2 Light diffusing agent, light diffusing resin composition and molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-16 US disclosed
US-20190031799-A1 LIGHT DIFFUSING AGENT, LIGHT DIFFUSING RESIN COMPOSITION AND MOLDED BODY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2019-01-31 US disclosed
EP-3413102-A1 LIGHT DIFFUSING AGENT, LIGHT DIFFUSING RESIN COMPOSITION AND MOLDED BODY Mitsubishi Gas Chemical Company, Inc. (JP) 2018-12-12 EP disclosed