Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811081 | 0.80 | NAALAD2 (0.45) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL28184813 | 0.79 | ALDH1A1 (0.42) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL12410508 | 0.78 | NAALAD2 (0.43) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL21989009 | 0.77 | ALDH1A1 (0.41) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL8061584 | 0.76 | NAALAD2 (0.42) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL20374757 | 0.76 | NAALAD2 (0.38) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL11403557 | 0.74 | NAALAD2 (0.41) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL24168564 | 0.74 | ALDH1A1 (0.42) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL12945252 | 0.74 | NAALAD2 (0.37) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL12944268 | 0.74 | NAALAD2 (0.37) | NAALAD2ALDH1A1MEN1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634430-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018226732-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2018-12-13 | — | — | WO | disclosed |