Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20587603 | 1.00 | KDM4E (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL22179481 | 1.00 | KDM4E (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL683833 | 0.89 | KDM4E (0.67) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL14898605 | 0.87 | MAPT (0.65) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL22179516 | 0.86 | MAPT (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL20587680 | 0.86 | MAPT (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL20587677 | 0.86 | MAPT (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL30067012 | 0.86 | MAPT (0.73) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL6571628 | 0.85 | KDM4E (0.74) | KDM4ESMN1; SMN2LMNAKMT2AHTT | |
| SCHEMBL6571625 | 0.85 | KDM4E (0.74) | KDM4ESMN1; SMN2LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12325678-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-10 | — | — | US | disclosed |
| US-20240124392-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-04-18 | — | — | US | disclosed |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-12-15 | — | — | US | disclosed |
| US-11414378-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-08-16 | — | — | US | disclosed |
| US-20200207705-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-07-02 | — | — | US | disclosed |
| EP-3638649-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | The Research Foundation for The State University of New York (US) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018232298-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | KDM4E 1377/4885SMN1; SMN2 4407/4885LMNA 3665/4885 |
| US-12325678-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, SMPD1 | KDM4E 1113/4885SMN1; SMN2 4282/4885LMNA 3582/4885 |
| US-20200207705-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | KDM4E 1377/4885SMN1; SMN2 4407/4885LMNA 3665/4885 |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | KDM4E 1377/4885SMN1; SMN2 4407/4885LMNA 3665/4885 |
| US-20240124392-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | KDM4E 1377/4885SMN1; SMN2 4407/4885LMNA 3665/4885 |
| US-11414378-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, LSS | KDM4E 1060/4885SMN1; SMN2 4406/4885LMNA 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.