Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179546 | 1.00 | PIK3CG (0.60) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL20587714 | 1.00 | PIK3CG (0.60) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL20587597 | 0.86 | PIK3CG (0.60) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL20587598 | 0.86 | PIK3CG (0.60) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL22179543 | 0.86 | PIK3CG (0.60) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL26974401 | 0.84 | PIK3CG (0.79) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL20587712 | 0.84 | PIK3CG (0.57) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL22179619 | 0.84 | PIK3CG (0.57) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL20587710 | 0.84 | PIK3CG (0.57) | PIK3CGSIRT1MEN1KMT2AMAPT | |
| SCHEMBL684793 | 0.83 | PIK3CG (0.63) | PIK3CGSIRT1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12325678-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-10 | — | — | US | disclosed |
| US-20240124392-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-04-18 | — | — | US | disclosed |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-12-15 | — | — | US | disclosed |
| US-11414378-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-08-16 | — | — | US | disclosed |
| US-20200207705-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-07-02 | — | — | US | disclosed |
| EP-3638649-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | The Research Foundation for The State University of New York (US) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018232298-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | PIK3CG 488/4885SIRT1 2412/4885MEN1 1341/4885 |
| US-12325678-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, SMPD1 | PIK3CG 383/4885SIRT1 2281/4885MEN1 952/4885 |
| US-20200207705-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | PIK3CG 488/4885SIRT1 2412/4885MEN1 1341/4885 |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | PIK3CG 488/4885SIRT1 2412/4885MEN1 1341/4885 |
| US-20240124392-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | PIK3CG 488/4885SIRT1 2412/4885MEN1 1341/4885 |
| US-11414378-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, LSS | PIK3CG 378/4885SIRT1 2138/4885MEN1 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.