Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256347 | 0.82 | SLC6A4 (0.46) | HTR6SLC6A4HTR2CSLC6A2SLC6A3 | |
| SCHEMBL12064953 | 0.81 | IDO1 (0.51) | HTR6SLC6A2SLC6A3 | |
| SCHEMBL3130007 | 0.81 | HRH1 (0.50) | HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29117311 | 0.81 | HRH1 (0.50) | HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12064970 | 0.80 | HTR6 (0.46) | HTR6SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL18428982 | 0.80 | HRH1 (0.49) | HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10460455 | 0.76 | HTR6 (0.50) | HTR6SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL10461245 | 0.75 | HTR6 (0.49) | HTR6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14825679 | 0.73 | IDO1 (0.50) | HTR6SLC6A4HTR2CSLC6A2SLC6A3 | |
| SCHEMBL29148827 | 0.71 | AOC3 (0.49) | HTR6SLC6A4HTR2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018229683-A1 | 5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2018-12-20 | — | — | WO | disclosed |