Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.63 |
| ▸ | CA1 | P00915 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095965 | 0.86 | CA2 (0.66) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL16389960 | 0.85 | CA2 (0.63) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL2058687 | 0.84 | CA2 (0.68) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL27118233 | 0.83 | USP2 (0.52) | CA2CA1USP2MEN1ALDH1A1 | |
| SCHEMBL13811078 | 0.83 | CA2 (0.53) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL25732354 | 0.82 | CA2 (0.66) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL7981241 | 0.82 | CA2 (0.51) | CA2CA1MAPK1ALDH1A1MMP1 | |
| SCHEMBL5936918 | 0.81 | CA2 (0.60) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL5279569 | 0.81 | CA2 (0.60) | CA2CA1MAPK1USP2MEN1 | |
| SCHEMBL353712 | 0.81 | CA2 (0.60) | CA2CA1MAPK1USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968750-B2 | Process for producing nitrogen-containing compounds | KAO CORPORATION (JP) | 2011-06-28 | — | — | US | claimed |
| WO-2023220131-A2 | PI3Kα INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |