Acridan

Acridan

SCHEMBL20594012

c1ccc2c(c1)Cc1ccccc1N2.c1ccc2c(c1)Cc1ccccc1N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
NPC1 O15118 2/20 0.65
KDM4E B2RXH2 2/20 0.65
AHR P35869 1/20 0.65
PDK2 Q15119 1/20 0.65
HSP90AA1 P07900 1/20 0.65
THRB P10828 1/20 0.65
HK1 P19367 1/20 0.65
MAPK1 P28482 1/20 0.65
RECQL P46063 1/20 0.65
RAB9A P51151 1/20 0.65
GALK1 P51570 1/20 0.65
BLM P54132 1/20 0.65
HKDC1 Q2TB90 1/20 0.65
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 1/20 0.58
BRD4 O60885 2/20 0.50
CREBBP Q92793 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridan SCHEMBL29446489 1.00 MAPT (0.65) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL29405807 1.00 MAPT (0.65) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL183367 1.00 MAPT (0.65) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL29006126 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL29020974 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
SCHEMBL4571016 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL15412652 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL28832553 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL10813635 0.97 MAPT (0.62) MAPTMEN1KMT2ANPC1KDM4E
Acridan SCHEMBL4012624 0.95 MAPT (0.60) MAPTMEN1KMT2ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11214636-B2 Rigid non-cyclopentadienyl group 4 transition metal and rare earth metal catalysts for olefin polymerization MCMASTER UNIVERSITY (CA) 2022-01-04 US disclosed
US-20200308322-A1 RIGID NON-CYCLOPENTADIENYL GROUP 4 TRANSITION METAL AND RARE EARTH METAL CATALYSTS FOR OLEFIN POLYMERIZATION MCMASTER UNIVERSITY (CA) 2020-10-01 US disclosed
WO-2018232503-A1 RIGID NON-CYCLOPENTADIENYL GROUP 4 TRANSITION METAL AND RARE EARTH METAL CATALYSTS FOR OLEFIN POLYMERIZATION MCMASTER UNIVERSITY (CA) 2018-12-27 WO disclosed