Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 1.00 |
| ▸ | CRBN | Q96SW2 | 14/20 | 1.00 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738828 | 1.00 | DDB1 (1.00) | DDB1CRBNGPR119WNT3AMAP4K4 | |
| SCHEMBL21903080 | 1.00 | DDB1 (1.00) | DDB1CRBNGPR119WNT3AMAP4K4 | |
| SCHEMBL23783372 | 0.95 | DDB1 (0.91) | DDB1CRBNGPR119 | |
| SCHEMBL31329768 | 0.95 | DDB1 (0.91) | DDB1CRBNGPR119 | |
| SCHEMBL23538408 | 0.87 | DDB1 (0.77) | DDB1CRBNGPR119 | |
| SCHEMBL30888791 | 0.87 | DDB1 (0.77) | DDB1CRBNGPR119 | |
| SCHEMBL25632051 | 0.86 | DDB1 (0.75) | DDB1CRBNGPR119 | |
| SCHEMBL20595405 | 0.85 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL20595430 | 0.85 | DDB1 (0.74) | DDB1CRBNGPR119 | |
| SCHEMBL30120110 | 0.85 | DDB1 (0.74) | DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3641762-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2020-04-29 | — | — | EP | disclosed |
| WO-2018237026-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2018-12-27 | — | — | WO | disclosed |