Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS2 | Q96GW9 | 11/20 | 0.71 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.33 |
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | CDK4 | P11802 | 4/20 | 0.31 |
| ▸ | CCND1 | P24385 | 4/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.31 |
| ▸ | CDK1 | P06493 | 3/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23419412 | 0.86 | MARS2 (0.53) | MARS2CCNE2CCNE1CDK2CDK4 | |
| SCHEMBL20595910 | 0.86 | MARS2 (0.80) | MARS2FPR2 | |
| SCHEMBL20596040 | 0.83 | MARS2 (1.00) | MARS2 | |
| SCHEMBL20596125 | 0.82 | MARS2 (1.00) | MARS2FPR2P2RX7 | |
| SCHEMBL20595884 | 0.77 | MARS2 (0.86) | MARS2ADORA2B | |
| SCHEMBL20595839 | 0.76 | MARS2 (0.64) | MARS2 | |
| SCHEMBL20595915 | 0.76 | MARS2 (0.85) | MARS2 | |
| SCHEMBL20595966 | 0.75 | MARS2 (0.77) | MARS2 | |
| SCHEMBL20595907 | 0.75 | MARS2 (0.83) | MARS2ADORA2B | |
| SCHEMBL20596217 | 0.75 | MARS2 (1.00) | MARS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018237349-A1 | INHIBITORS OF TYPED 1 METHIONYL-TRNA SYNTHETASE AND METHODS OF USING THEM | UNIVERSITY OF WASHINGTON (US) | 2018-12-27 | — | — | WO | claimed |