Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL20599554

N.c1ccc(-c2cccnc2-c2ccccc2)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.64
PTGS1 P23219 1/20 0.64
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HTT P42858 1/20 0.50
PTPRC P08575 2/20 0.47
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
PTPN13 Q12923 1/20 0.47
FEN1 P39748 1/20 0.47
TDP2 O95551 1/20 0.46
NSD2 O96028 1/20 0.46
ABL1 P00519 1/20 0.46
PLCG1 P19174 1/20 0.46
CES1 P23141 1/20 0.46
PAX8 Q06710 1/20 0.46
RIN1 Q13671 1/20 0.46
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37278 0.98 PTGS2 (0.66) PTGS2PTGS1ALDH1A1HSD17B10HTT
Phosphine SCHEMBL29108837 0.95 PTGS2 (0.64) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL3344343 0.95 PTGS2 (0.64) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL29227428 0.95 PTGS2 (0.64) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL30021842 0.95 PTGS2 (0.64) PTGS2PTGS1ALDH1A1HSD17B10HTT
Hydrazine SCHEMBL29197518 0.93 PTGS2 (0.62) PTGS2PTGS1ALDH1A1HSD17B10HTT
Pyrazine SCHEMBL28393900 0.91 PTGS2 (0.60) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL7647031 0.91 PTGS2 (0.58) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL21692150 0.91 PTGS1 (0.58) PTGS2PTGS1ALDH1A1HSD17B10HTT
SCHEMBL17578934 0.90 PTGS2 (0.58) PTGS2PTGS1ALDH1A1HSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933511-B Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2023-02-24 CN claimed
CN-114933511-A Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2022-08-23 CN claimed
CN-117777163-A Super alkali, preparation method and application 北京大学深圳研究生院 2024-03-29 CN disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
CN-117069643-A Novel free radical monomer containing diphenylamine derivative structure, polymer, preparation method and application thereof 武汉理工大学 2023-11-17 CN disclosed
CN-114933511-B Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2023-02-24 CN disclosed
CN-115057892-A Metal organic complex and application thereof 北京云基科技有限公司 2022-09-16 CN disclosed
CN-114933511-A Method for quickly converting carboxyl into aldehyde group 中国科学院兰州化学物理研究所 2022-08-23 CN disclosed
CN-113201019-A Organic electroluminescent material and device 环球展览公司 2021-08-03 CN disclosed
CN-111527094-A Compound having boron as spiro atom and polymer compound thereof 学校法人关西学院 2020-08-11 CN disclosed
CN-106795191-B Novel precatalyst scaffolds for crosslinking reactions and methods of making and using same 耶鲁大学 2020-07-03 CN disclosed
CN-111282598-A Novel precatalyst scaffolds for crosslinking reactions and methods of making and using same 耶鲁大学 2020-06-16 CN disclosed
WO-2019000024-A1 HIGHLY EMISSIVE PYRIDINIUM ENOLATES THE UNIVERSITY OF MELBOURNE (AU) 2019-01-03 WO disclosed
CN-104125946-B The disease that 6-aminopyridine-3-01 derivatives or its pharmaceutically acceptable salt and prevention or treatment are caused by angiogenesis, containing above-mentioned substance as the pharmaceutical composition of active component 岭南大学校产学协力团 2016-09-28 CN disclosed