Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135636 | 0.66 | — | — | |
| SCHEMBL1682326 | 0.62 | — | — | |
| SCHEMBL23706655 | 0.61 | TRIM24 (0.35) | SMN1; SMN2 | |
| Cyclohexane SCHEMBL27829858 | 0.60 | KDM4E (0.67) | KMT2A | |
| Dimethyl Sulfone SCHEMBL1813999 | 0.60 | — | — | |
| Cyclohexanone SCHEMBL670911 | 0.58 | TRIM24 (0.61) | KMT2A | |
| SCHEMBL18393768 | 0.58 | — | — | |
| Trimethylammonium SCHEMBL27805383 | 0.58 | TRIM24 (0.73) | KMT2ASMN1; SMN2 | |
| Cyclohexanone SCHEMBL27426815 | 0.58 | TRIM24 (0.73) | KMT2ASMN1; SMN2 | |
| SCHEMBL23706714 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645516-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | Janssen Pharmaceutica NV (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019001420-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |