Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988053 | 0.86 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BADORA3PIK3CD | |
| SCHEMBL12077150 | 0.83 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL11370598 | 0.82 | MEN1 (0.44) | ADORA2AADORA1PIK3CDRAB9AALDH1A1 | |
| SCHEMBL20600732 | 0.81 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BALDH1A1MEN1 | |
| SCHEMBL20600555 | 0.80 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BALDH1A1MEN1 | |
| SCHEMBL3063909 | 0.80 | ADORA2A (0.43) | ADORA2AADORA1ADORA2BPIK3CDMAPK14 | |
| SCHEMBL11369579 | 0.79 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BADORA3MAPK14 | |
| SCHEMBL17416946 | 0.78 | PTPN11 (0.42) | ADORA2AADORA1 | |
| SCHEMBL20658598 | 0.75 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BMAPK14MAPK11 | |
| SCHEMBL29832087 | 0.75 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BMAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747255-A1 | MODULATORS OF THE ADENOSINE A2A AND A2B RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025018901-A1 | MODULATORS OF THE ADENOSINE A2A AND A2B RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2025-01-23 | — | — | WO | disclosed |
| US-20200369665-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-11-26 | — | — | US | disclosed |
| WO-2020128036-A1 | MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020128036-A1 | MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-06-25 | — | — | WO | disclosed |
| EP-3645536-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-05-06 | — | — | EP | disclosed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |
| WO-2019002606-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | SELVITA S.A. (PL) | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369665-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ADORA1 2/4885ADORA2B 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.