Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154780 | 1.00 | RAB9A (0.51) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8154779 | 1.00 | RAB9A (0.51) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11258728 | 1.00 | RAB9A (0.51) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9682651 | 0.81 | RAB9A (0.49) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9682645 | 0.81 | RAB9A (0.49) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8647851 | 0.76 | RAB9A (0.45) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11636581 | 0.75 | CCR6 (0.33) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11636584 | 0.75 | CCR6 (0.33) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL12813288 | 0.72 | RAB9A (0.42) | RAB9AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL12813289 | 0.72 | RAB9A (0.42) | RAB9AALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005841-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-01-03 | — | — | WO | disclosed |