Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNK | O75909 | 2/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060179 | 0.88 | TLR7 (0.52) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL2060341 | 0.86 | ADORA2A (0.45) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL2060202 | 0.84 | ADORA2A (0.63) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL2060288 | 0.82 | CDK1 (0.58) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL2060338 | 0.80 | TLR7 (0.52) | TLR7 | |
| SCHEMBL28929629 | 0.79 | TMIGD3 (0.56) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL4458518 | 0.78 | TLR7 (0.65) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL31042226 | 0.78 | TLR7 (0.65) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| Bromide SCHEMBL3134008 | 0.78 | TMIGD3 (0.55) | TLR7ADORA2AADORA1ADORA2BTMIGD3 | |
| SCHEMBL18584238 | 0.78 | ADORA2A (0.59) | TLR7ADORA2AADORA1ADORA2BTMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-8148371-B2 | Adenine compound and use thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO.,LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-1550662-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256118-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, P2RY10, HRH4 | TLR7 265/4885ADORA2A 6/4885ADORA1 1/4885 |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | TLR7 252/4885ADORA2A 4/4885ADORA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.