Cholesterol

Cholesterol

SCHEMBL20607477

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OSBP P22059 6/20 1.00
RORC P51449 5/20 1.00
OSBP2 Q969R2 3/20 1.00
USP2 O75604 1/20 1.00
LMNA P02545 1/20 1.00
ABCB1 P08183 1/20 1.00
CYP46A1 Q9Y6A2 1/20 1.00
GRIN1 Q05586 6/20 0.85
GRIN2A Q12879 6/20 0.85
NR1H3 Q13133 7/20 0.84
CRYAB P02511 1/20 0.80
HMGCR P04035 1/20 0.80
ITGB3 P05106 1/20 0.80
ITGAV P06756 1/20 0.80
SREBF2 Q12772 1/20 0.80
NPC1L1 Q9UHC9 1/20 0.80
GRIN2B Q13224 5/20 0.80
DHCR24 Q15392 1/20 0.77
EPHA2 P29317 1/20 0.75
NR1H2 P55055 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cholesterol SCHEMBL21707472 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL21539517 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL22095727 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL21447271 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL23579652 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL21340667 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL23365796 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL21650234 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL23761109 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA
Cholesterol SCHEMBL21445079 1.00 OSBP (1.00) OSBPRORCOSBP2USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498272-B1 OXYBUTYNIN-CONTAINING TRANSDERMAL ABSORPTION PREPARATION HISAMITSU PHARMACEUTICAL CO (JP) 2024-01-31 EP disclosed
EP-3350333-B1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNATX INC (US) 2021-10-27 EP disclosed
WO-2020066158-A1 FAT ACCUMULATION INHIBITOR AND BLOOD LIPID LEVEL IMPROVING AGENT アサヒグループホールディングス株式会社 2020-04-02 WO disclosed
US-20190216746-A1 OXYBUTYNIN-CONTAINING TRANSDERMAL ABSORPTION PREPARATION HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2019-07-18 US disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
EP-3498272-A1 OXYBUTYNIN-CONTAINING TRANSDERMAL ABSORPTION PREPARATION Hisamitsu Pharmaceutical Co., Inc. (JP) 2019-06-19 EP disclosed
EP-3461904-A1 ALTERNATIVE NUCLEIC ACID MOLECULES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF ModernaTX, Inc. (US) 2019-04-03 EP disclosed
EP-3041948-B1 ALTERNATIVE NUCLEIC ACID MOLECULES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF MODERNATX INC (US) 2019-01-09 EP disclosed
CN-203789061-U SCGF food supplement capsule for improving liver injury GWOXI STEM CELL APPLIED TECHNOLOGY CO LTD 2014-08-27 CN disclosed