Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | RB1 | P06400 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20608227 | 1.00 | SLC18A3 (0.62) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL20321172 | 1.00 | SLC18A3 (0.62) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL22139619 | 0.91 | EPHX1 (0.64) | SLC18A3PDPK1EPHX1BCHEACHE | |
| SCHEMBL9226618 | 0.91 | EPHX1 (0.60) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL2322457 | 0.85 | PDPK1 (0.70) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL5690934 | 0.84 | SLC18A3 (0.50) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL20061132 | 0.84 | SLC18A3 (0.79) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL20061144 | 0.84 | SLC18A3 (0.79) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| SCHEMBL5690967 | 0.83 | PDPK1 (0.54) | SLC18A3PDPK1MAOAMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL7123292 | 0.83 | PDPK1 (0.68) | SLC18A3PDPK1MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190009259-A1 | LIGANDS AND CATALYSTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190009259-A1 | LIGANDS AND CATALYSTS | LSS, DCXR, CYP2F1 | SLC18A3 3044/4885PDPK1 4610/4885MAOA 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.