Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690934 | 0.94 | SLC18A3 (0.50) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL20608227 | 0.83 | SLC18A3 (0.62) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL20321172 | 0.83 | SLC18A3 (0.62) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL20608209 | 0.83 | SLC18A3 (0.62) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL2322457 | 0.82 | PDPK1 (0.70) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| Hydrochloric Acid SCHEMBL7123292 | 0.80 | PDPK1 (0.68) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL4209025 | 0.79 | PDPK1 (0.57) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL12431685 | 0.78 | SLC18A3 (0.52) | PDPK1KDM1AMAOAMAOBSLC18A3 | |
| SCHEMBL3853169 | 0.76 | HTR2C (0.53) | CA1CA2HTR6HTR2C | |
| SCHEMBL3316700 | 0.75 | EPHX1 (0.50) | PDPK1SLC18A3ADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658269-A1 | FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | Abbott Laboratories (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2004111009-A1 | FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LABORATORIES (US) | 2004-12-23 | — | — | WO | disclosed |