Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 3/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 3/20 | 1.00 |
| ▸ | ADRB3 | P13945 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766867 | 1.00 | KMT2A (1.00) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| SCHEMBL3692842 | 1.00 | KMT2A (1.00) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| SCHEMBL30541631 | 1.00 | KMT2A (1.00) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL2334376 | 0.99 | KMT2A (0.98) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL29429320 | 0.96 | KMT2A (0.92) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL16162598 | 0.96 | KMT2A (0.92) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL14354386 | 0.96 | KMT2A (0.92) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9537333 | 0.87 | KMT2A (0.77) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9540272 | 0.87 | KMT2A (0.77) | KMT2AMEN1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9533664 | 0.87 | ADRB2 (0.76) | KMT2AMEN1CYP1A2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010548-A1 | METHODS AND MATERIALS FOR DETERMINING PAIN SENSITIVITY AND PREDICTING AND TREATING RELATED DISORDERS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2019-01-10 | — | — | US | claimed |
| US-20250281447-A1 | SIGMA-1 RECEPTOR AGONIST SYSTOLIC BLOOD PRESSURE THERAPY | ANAVEX LIFE SCIENCES CORP. | 2025-09-11 | — | — | US | disclosed |
| CN-111712241-B | Sigma-1 receptor agonist systolic blood pressure therapy | 阿纳韦克斯生命科学公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023159253-A2 | ALPHA 2 ADRENERGIC RECEPTOR BLOCKADE FOR THE TREATMENT OF C. DIFFICILE COLITIS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-08-24 | — | — | WO | disclosed |
| US-11622955-B2 | Sigma-1 receptor agonist systolic blood pressure therapy | ANAVEX LIFE SCIENCES CORP. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20230071766-A1 | SIGMA-1 RECEPTOR AGONIST SYSTOLIC BLOOD PRESSURE THERAPY | ANAVEX LIFE SCIENCES CORP. (US) | 2023-03-09 | — | — | US | disclosed |
| US-20210186920-A1 | SIGMA-1 RECEPTOR AGONIST SYSTOLIC BLOOD PRESSURE THERAPY | ANAVEX LIFE SCIENCES CORP. (US) | 2021-06-24 | — | — | US | disclosed |
| CN-111712241-A | Sigma-1 receptor agonist systolic blood pressure therapy | 阿纳韦克斯生命科学公司 | 2020-09-25 | — | — | CN | disclosed |