Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17172233 | 0.87 | CYP19A1 (0.42) | LMNAHTTCYP19A1KMT2ACYP3A4 | |
| SCHEMBL17157474 | 0.87 | CYP3A4 (0.45) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20052093 | 0.84 | SYK (0.32) | — | |
| SCHEMBL17172238 | 0.84 | MAP4K4 (0.39) | ACACBCYP19A1 | |
| SCHEMBL17157449 | 0.84 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17172248 | 0.84 | CYP19A1 (0.37) | CYP19A1CYP3A4 | |
| SCHEMBL17172203 | 0.83 | ALOX5AP (0.35) | ACACBKDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17196173 | 0.83 | CYP19A1 (0.47) | ALDH1A1CYP19A1MEN1KMT2A | |
| SCHEMBL17172249 | 0.83 | ATM (0.41) | CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL17172234 | 0.83 | KIF11 (0.43) | KDM4EMAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | ACACB 1922/4885CHRNA7 3423/4885KDM4E 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.