Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28621414 | 0.88 | GRIK1 (0.54) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL27636120 | 0.88 | GRIK1 (0.54) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL28626388 | 0.88 | GRIK1 (0.54) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL28621418 | 0.88 | GRIK1 (0.54) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL6942687 | 0.88 | GRIK1 (0.54) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL5687634 | 0.76 | GRIK1 (0.41) | GRIK1GPR84FFAR4FFAR1EP300 | |
| SCHEMBL1506722 | 0.73 | FFAR1 (0.52) | GPR84FFAR4FFAR1FAAHPTPN1 | |
| SCHEMBL1506742 | 0.73 | FFAR1 (0.52) | GPR84FFAR4FFAR1FAAHPTPN1 | |
| SCHEMBL1506724 | 0.73 | FFAR1 (0.52) | GPR84FFAR4FFAR1FAAHPTPN1 | |
| SCHEMBL1506743 | 0.73 | FFAR1 (0.52) | GPR84FFAR4FFAR1FAAHPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555021-B2 | Fatty acid derivatives and their use | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-01-17 | — | — | US | disclosed |
| US-20220274940-A1 | FATTY ACID DERIVATIVES AND THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (US) | 2022-09-01 | — | — | US | disclosed |
| US-20210139440-A1 | FATTY ACID DERIVATIVES AND THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2021-05-13 | — | — | US | disclosed |
| EP-3649115-A1 | FATTY ACID DERIVATIVES AND THEIR USE | The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019010414-A1 | FATTY ACID DERIVATIVES AND THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139440-A1 | FATTY ACID DERIVATIVES AND THEIR USE | FFAR3, FFAR1, FFAR2 | GRIK1 326/4885GPR84 125/4885FFAR4 4/4885 |
| US-20220274940-A1 | FATTY ACID DERIVATIVES AND THEIR USE | FFAR3, FFAR1, FFAR2 | GRIK1 326/4885GPR84 125/4885FFAR4 4/4885 |
| US-11555021-B2 | Fatty acid derivatives and their use | FFAR3, FFAR1, FFAR2 | GRIK1 326/4885GPR84 125/4885FFAR4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.