Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611260 | 0.85 | CNR2 (0.44) | CNR2 | |
| SCHEMBL20998151 | 0.81 | HRH4 (0.39) | CNR2 | |
| SCHEMBL20998150 | 0.79 | CNR2 (0.47) | CNR2 | |
| SCHEMBL20611081 | 0.79 | CNR2 (0.47) | CNR2 | |
| SCHEMBL20611053 | 0.76 | CNR2 (0.61) | CNR2 | |
| SCHEMBL20611078 | 0.75 | CNR2 (0.49) | CNR2 | |
| SCHEMBL20611315 | 0.75 | CNR2 (0.61) | CNR2 | |
| SCHEMBL20611157 | 0.74 | CNR2 (0.63) | CNR2 | |
| SCHEMBL20610986 | 0.72 | CNR2 (0.65) | CNR2 | |
| SCHEMBL23544261 | 0.72 | CNR2 (0.56) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943497-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3483163-A2 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2019-05-15 | — | — | EP | disclosed |
| EP-3041843-B1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2019-01-02 | — | — | EP | disclosed |