Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 17/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611081 | 0.91 | CNR2 (0.47) | CNR2 | |
| SCHEMBL20998150 | 0.91 | CNR2 (0.47) | CNR2 | |
| SCHEMBL20610992 | 0.81 | CNR2 (0.47) | CNR2 | |
| SCHEMBL23544253 | 0.74 | CNR2 (0.51) | CNR2 | |
| SCHEMBL20611271 | 0.70 | CNR2 (0.57) | CNR2 | |
| SCHEMBL20611153 | 0.68 | CNR2 (0.49) | CNR2 | |
| SCHEMBL20611000 | 0.68 | CNR2 (0.68) | CNR2 | |
| SCHEMBL23544240 | 0.67 | CNR2 (0.66) | CNR2 | |
| SCHEMBL20611260 | 0.67 | CNR2 (0.44) | CNR2 | |
| SCHEMBL23544260 | 0.61 | CNR2 (0.63) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943497-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3483163-A2 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2019-05-15 | — | — | EP | disclosed |