Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968872 | 1.00 | TRPV4 (0.31) | TRPV4PTPN11 | |
| SCHEMBL20714135 | 0.91 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL20597286 | 0.85 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL20714069 | 0.84 | CCR1 (0.32) | TRPV4 | |
| SCHEMBL20714056 | 0.84 | KCNH2 (0.31) | TRPV4 | |
| SCHEMBL28967722 | 0.81 | KRAS (0.34) | — | |
| SCHEMBL20597450 | 0.81 | KRAS (0.34) | — | |
| SCHEMBL28967723 | 0.81 | KRAS (0.34) | — | |
| SCHEMBL20597189 | 0.80 | MAPT (0.37) | TRPV4 | |
| SCHEMBL20597573 | 0.80 | AKT2 (0.31) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851079-B2 | Piperidine derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20190040039-A1 | PIPERIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-3421454-A1 | PIPERIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2019-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851079-B2 | Piperidine derivative | EP300, SLC11A2, TBC1D5 | TRPV4 814/4885PTPN11 1081/4885 |
| US-20190040039-A1 | PIPERIDINE DERIVATIVE | EP300, SLC11A2, TBC1D5 | TRPV4 814/4885PTPN11 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.