Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253589 | 0.84 | HTR2C (0.55) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7253595 | 0.84 | HTR2C (0.55) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7253587 | 0.84 | HTR2C (0.55) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL24142902 | 0.81 | HTR7 (0.63) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7253255 | 0.80 | PRMT5 (0.48) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL27642179 | 0.77 | HTR2C (0.48) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7258385 | 0.76 | HTR2C (0.50) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7258397 | 0.75 | HTR2C (0.52) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL7258395 | 0.75 | HTR2C (0.52) | HTR7PRMT5HTR2CHTR2APRMT1 | |
| SCHEMBL20612088 | 0.74 | SMN1; SMN2 (0.67) | HTR7PSMB1PSMB5NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019001572-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | 北京泰德制药股份有限公司 | 2019-01-03 | — | — | WO | disclosed |