Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | UTS2R | Q9UKP6 | 13/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20601472 | 0.89 | KDM4E (0.56) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601297 | 0.89 | KDM4E (0.58) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601295 | 0.89 | KDM4E (0.58) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20618746 | 0.87 | KDM4E (0.54) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601301 | 0.86 | KDM4E (0.53) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20618556 | 0.85 | KDM4E (0.55) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20618744 | 0.85 | KDM4E (0.55) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601405 | 0.85 | KDM4E (0.52) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601224 | 0.85 | UTS2R (0.55) | KDM4EGAAUTS2RITGB3ITGA2B | |
| SCHEMBL20601520 | 0.85 | ALDH1A1 (0.54) | KDM4EGAAUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019003142-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-03 | — | — | WO | disclosed |