SCHEMBL2062004

SCHEMBL2062004

c1ccc(-c2cnccn2)nc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.67
LMNA P02545 3/20 0.67
CCR1 P32246 3/20 0.67
CCR5 P51681 3/20 0.67
CCR8 P51685 3/20 0.67
METAP1 P53582 3/20 0.67
P4HTM Q9NXG6 2/20 0.67
CYP1A2 P05177 1/20 0.67
POLB P06746 1/20 0.67
BLM P54132 1/20 0.67
HIF1A Q16665 1/20 0.67
DOHH Q9BU89 1/20 0.67
CYP2A6 P11509 1/20 0.57
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
TP53 P04637 3/20 0.56
HTT P42858 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ALOX15 P16050 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907668 1.00 KDM4E (0.67) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31140235 1.00 KDM4E (0.67) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6050743 1.00 KDM4E (0.67) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27946179 0.92 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL19944117 0.92 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL28077341 0.89 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL4904857 0.85 KDM4E (0.82) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL30476148 0.84 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
SCHEMBL22147393 0.82 NPC1 (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21560727 0.82 CYP2A6 (0.46) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240349602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-10-17 US claimed
CN-117843661-A Preparation, structure and fluorescence application of two mononuclear zinc complexes 桂林理工大学 2024-04-09 CN claimed
CN-117551136-A 4-phenyl-2, 6-bis (2' -pyrazinyl) pyridine binuclear platinum complex, synthesis method and application 玉林师范学院 2024-02-13 CN claimed
CN-115449860-A Nickel-gold electroplating solution for ceramic substrate and electroplating process thereof 深圳市创智成功科技有限公司 2022-12-09 CN claimed
CN-112625068-B Preparation, structure and fluorescence of heterobinuclear nickel-europium complex 桂林理工大学 2022-09-30 CN claimed
CN-110922433-B 4-p-chlorophenyl-2, 6-di (2-pyrazinyl) pyridine and iron (II) complex as well as preparation and application thereof 西北师范大学 2022-06-14 CN claimed
CN-112625068-A Preparation, structure and fluorescence of heterobinuclear nickel-europium complex 桂林理工大学 2021-04-09 CN claimed
CN-111647008-A Preparation, structure and fluorescent application of tppz bridged binuclear europium complex 桂林理工大学 2020-09-11 CN claimed
CN-110922433-A 4-p-chlorophenyl-2, 6-di (2-pyrazinyl) pyridine and iron (II) complex as well as preparation and application thereof 西北师范大学 2020-03-27 CN claimed
CN-101878031-A The inhibitors of kinases that is used for the treatment of myeloproliferative disease and other proliferative diseases DECIPHERA PHARMACEUTICALS LLC 2010-11-03 CN claimed
CN-101801383-A Kinase inhibitors for the treatment of myeloproliferative and other proliferative diseases DECIPHERA PHARMACEUTICALS LLC 2010-08-11 CN claimed
CN-1823042-B Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines CIBA SC HOLDING AG 2010-06-23 CN claimed
CN-101553232-A Kinase inhibitors useful for the treatment of proliferative diseases DECIPHERA PHARMACEUTICALS LLC (US) 2009-10-07 CN claimed
CN-101553233-A Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases DECIPHERA PHARMACEUTICALS LLC (US) 2009-10-07 CN claimed
WO-2008145835-A2 METHOD FOR HYDROGENATING AN AROMATIC CHARGE USING AS A CATALYST A SUSPENSION OF METAL NANOPARTICLES CONTAINING A NITROGEN LIGAND IN AN IONIC LIQUID I.F.P. (FR) 2008-12-04 WO claimed
CN-1823042-A Hydrogen peroxide catalyzed process for the preparation of sterically hindered n-hydrocarbyloxyamines CIBA SC HOLDING AG (CH) 2006-08-23 CN claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-5302531-A Mixture of complexing agent, metal compound and indicator MILES INC. (US) 1994-04-12 US claimed
US-4764454-A Color photographic material with color forming ligand compounds and a method of processing FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US claimed