⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20622919 | 0.77 | — | — | |
| SCHEMBL22003249 | 0.77 | — | — | |
| SCHEMBL330854 | 0.69 | — | — | |
| SCHEMBL15293162 | 0.64 | — | — | |
| SCHEMBL19361728 | 0.61 | — | — | |
| SCHEMBL15271455 | 0.61 | CA1 (0.35) | — | |
| SCHEMBL22642294 | 0.59 | — | — | |
| SCHEMBL11131465 | 0.59 | SLC22A2 (0.33) | — | |
| SCHEMBL4893281 | 0.59 | — | — | |
| SCHEMBL22642286 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005966-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |