⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20622919 | 1.00 | — | — | |
| SCHEMBL20622918 | 0.77 | — | — | |
| SCHEMBL3901374 | 0.67 | TRPA1 (0.40) | — | |
| SCHEMBL11131465 | 0.62 | SLC22A2 (0.33) | — | |
| SCHEMBL3911741 | 0.62 | — | — | |
| SCHEMBL21475420 | 0.59 | — | — | |
| SCHEMBL18467477 | 0.55 | — | — | |
| SCHEMBL17930574 | 0.55 | — | — | |
| SCHEMBL3913118 | 0.54 | HSD11B1 (0.33) | — | |
| SCHEMBL24612981 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229709-B2 | Dendrimer drug conjugates for sustained intra-articular delivery | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-01-25 | — | — | US | disclosed |
| US-20200155692-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | UNITED STATES GOVERNMENT | 2020-05-21 | — | — | US | disclosed |