Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284106 | 0.91 | KDM4E (0.42) | TLR7PARP1TLR8 | |
| SCHEMBL23553101 | 0.89 | HTR1A (0.41) | PARP1 | |
| SCHEMBL22445008 | 0.89 | CETP (0.41) | TLR7IP6K1PARP1MAP4K4TLR8 | |
| SCHEMBL29429800 | 0.89 | CETP (0.41) | TLR7IP6K1PARP1MAP4K4TLR8 | |
| SCHEMBL22180948 | 0.88 | TLR7 (0.36) | TLR7IP6K1PARP1MAP4K4TLR8 | |
| SCHEMBL20647762 | 0.88 | TLR7 (0.37) | TLR7IP6K1PARP1MAP4K4TLR8 | |
| Hydrochloric Acid SCHEMBL22445124 | 0.88 | CETP (0.41) | TLR7IP6K1PARP1MAP4K4TLR8 | |
| SCHEMBL22445151 | 0.87 | S1PR1 (0.36) | TLR7IP6K1PARP1TLR8 | |
| SCHEMBL24634187 | 0.86 | HTR1A (0.43) | PARP1 | |
| SCHEMBL24433888 | 0.84 | TLR7 (0.37) | TLR7PARP1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006038-A1 | METHODS AND COMPOSITIONS FOR DECTIN-2 STIMULATION AND CANCER IMMUNOTHERAPY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-01-03 | — | — | WO | disclosed |