Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809605 | 0.79 | TSHR (0.61) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL7853631 | 0.79 | TSHR (0.37) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL8799194 | 0.76 | — | — | |
| SCHEMBL17912275 | 0.76 | TSHR (0.47) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL996827 | 0.76 | — | — | |
| SCHEMBL10423 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL38659341 | 0.76 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3065183 | 0.76 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL3065185 | 0.76 | TSHR (0.58) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL4969564 | 0.74 | MEN1 (0.43) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676426-B2 | Acrylonitrile derivatives from epoxide and carbon monoxide reagents | NOVOMER, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190002400-A1 | Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents | NOVOMER, INC. (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10676426-B2 | Acrylonitrile derivatives from epoxide and carbon monoxide reagents | POR, AGL, ALK | TSHR 4838/4885GABRR1 3472/4885GABRR2 3569/4885 |
| US-20190002400-A1 | Acrylonitrile Derivatives from Epoxide and Carbon Monoxide Reagents | POR, AGL, ALK | TSHR 4838/4885GABRR1 3472/4885GABRR2 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.