Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 2/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 16/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 13/20 | 0.51 |
| ▸ | KDR | P35968 | 13/20 | 0.51 |
| ▸ | FLT1 | P17948 | 5/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28399198 | 0.91 | FGFR3 (0.54) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL30424992 | 0.91 | FGFR3 (0.54) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL20624902 | 0.91 | FGFR3 (0.54) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL20625616 | 0.91 | FGFR1 (0.62) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL23326256 | 0.91 | FGFR3 (0.68) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL23326253 | 0.91 | FGFR3 (0.60) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL20625529 | 0.91 | FGFR3 (0.68) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL23326078 | 0.91 | FGFR1 (0.62) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL20625528 | 0.91 | FGFR3 (0.68) | FGFR3FGFR1PDGFRBKDRFLT1 | |
| SCHEMBL20625447 | 0.91 | FGFR3 (0.60) | FGFR3FGFR1PDGFRBKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019001419-A1 | NEW QUINOLINONE COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |