Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234001 | 0.72 | CYP3A4 (0.81) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL19915769 | 0.71 | NLN (0.33) | — | |
| SCHEMBL16624730 | 0.66 | SMN1; SMN2 (0.48) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1881696 | 0.66 | CYP3A4 (0.97) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL8935259 | 0.65 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL16610098 | 0.65 | MAPT (0.84) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL20715213 | 0.65 | CYP3A4 (1.00) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL2812920 | 0.64 | CYP11B1 (0.66) | CYP3A4CYP2C9CYP1A2CYP2C19MAPT | |
| SCHEMBL17537295 | 0.64 | KMT2A (0.57) | MAPTLMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL20799451 | 0.64 | HPGD (0.46) | CYP3A4CYP1A2CYP2C19MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190002436-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002436-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | NR0B1, NR1I3, SCARB1 | CYP3A4 864/4885CYP2C9 2115/4885CYP1A2 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.