SCHEMBL2812920

SCHEMBL2812920

c1cncc(-c2c3ccccc3cc3ccccc23)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.66
GPR84 Q9NQS5 1/20 0.56
CYP11B2 P19099 4/20 0.55
CYP19A1 P11511 3/20 0.55
CYP17A1 P05093 1/20 0.55
ALDH1A1 P00352 5/20 0.52
CYP2A6 P11509 4/20 0.52
CYP1A2 P05177 3/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
HSD17B1 P14061 1/20 0.50
CYP2B6 P20813 1/20 0.50
CYP2C19 P33261 1/20 0.50
HSD17B2 P37059 1/20 0.50
KDM4E B2RXH2 5/20 0.46
MAPT P10636 4/20 0.46
HPGD P15428 4/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27845490 0.86 CYP11B1 (0.68) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL29515584 0.86 CYP2A6 (0.64) CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1
SCHEMBL13145318 0.86 CYP2A6 (0.64) CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1
SCHEMBL21788865 0.83 CYP11B1 (0.51) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL13146179 0.82 CYP11B1 (0.72) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL13146170 0.82 CYP11B1 (0.58) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL24662771 0.82 CYP2A6 (0.58) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL21808791 0.82 CYP11B1 (0.50) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL12887710 0.81 TNF (0.54) CYP11B1GPR84CYP11B2CYP19A1CYP17A1
SCHEMBL6240979 0.81 HPGD (0.55) CYP11B1CYP19A1ALDH1A1CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210184136-A1 ORGANIC LIGHT EMITTING DIODE FOR HIGH EFFICIENCY SFC CO LTD (KR) 2021-06-17 US disclosed
CN-109336784-B Soluble branch-substituted anthracene-based deep blue light material and preparation and application thereof 华南理工大学 2020-09-22 CN disclosed
CN-105884709-A Oxadiazole Derivative, Light Emitting Element Employing The Same, and Light Emitting Apparatus 株式会社半导体能源研究所 2016-08-24 CN disclosed
US-8859108-B2 Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-14 US disclosed
US-8859108-B2 Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-14 US disclosed
US-8859108-B2 Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-14 US disclosed
US-8481176-B2 Oxadiazole derivative, and light-emitting element, light-emitting device, electronic device, and lighting device using oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-07-09 US disclosed
US-8481176-B2 Oxadiazole derivative, and light-emitting element, light-emitting device, electronic device, and lighting device using oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-07-09 US disclosed
US-8481176-B2 Oxadiazole derivative, and light-emitting element, light-emitting device, electronic device, and lighting device using oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-07-09 US disclosed
CN-101851216-A Oxadiazole derivative, and electronic device and lighting device using same SEMICONDUCTOR ENERGY LAB 2010-10-06 CN disclosed
US-20100244673-A1 Oxadiazole Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-30 US disclosed
US-20100244673-A1 Oxadiazole Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-30 US disclosed
US-20100244673-A1 Oxadiazole Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-30 US disclosed
US-20090286985-A1 Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABARATORY CO., LTD. 2009-11-19 US disclosed
US-20090286985-A1 Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABARATORY CO., LTD. 2009-11-19 US disclosed
US-20090286985-A1 Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABARATORY CO., LTD. 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100244673-A1 Oxadiazole Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device Using Oxadiazole Derivative OXA1L, OXER1, DRD1 CYP11B1 238/4885GPR84 338/4885CYP11B2 187/4885
US-20090286985-A1 Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Same CYP4X1, XDH, GABRA5 CYP11B1 255/4885GPR84 1170/4885CYP11B2 240/4885
US-20210184136-A1 ORGANIC LIGHT EMITTING DIODE FOR HIGH EFFICIENCY ALDH1A2, ALDH1A1, CYBA CYP11B1 383/4885GPR84 3816/4885CYP11B2 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.