SCHEMBL20626953

SCHEMBL20626953

Cc1cc(-c2ccccc2[S+](C)[O-])ccc1-c1cnc(N)cn1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 20/20 0.60
ALOX5AP P20292 19/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15916285 0.87 FEN1 (0.72) FEN1ALOX5AP
SCHEMBL21089477 0.84 ALOX5AP (0.55) FEN1ALOX5AP
SCHEMBL20627407 0.77 FEN1 (0.57) FEN1ALOX5AP
SCHEMBL15917553 0.76 ALOX5AP (0.77) FEN1ALOX5AP
SCHEMBL20627377 0.76 FEN1 (0.74) FEN1ALOX5AP
SCHEMBL15917146 0.75 ALOX5AP (1.00) FEN1ALOX5AP
SCHEMBL20627356 0.75 FEN1 (0.69) FEN1ALOX5AP
SCHEMBL21089040 0.74 FEN1 (0.67) FEN1ALOX5AP
SCHEMBL20626909 0.74 FEN1 (0.67) FEN1ALOX5AP
SCHEMBL20627090 0.74 FEN1 (0.64) FEN1ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3070085-B1 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-01-09 EP disclosed