SCHEMBL21089477

SCHEMBL21089477

C[S+]([O-])c1ccccc1-c1ccc(-c2cnc(N)cn2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 19/20 0.55
FEN1 P39748 19/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20627230 0.87 FEN1 (0.53) ALOX5APFEN1
SCHEMBL20627514 0.86 FEN1 (0.56) ALOX5APFEN1
SCHEMBL20626953 0.84 FEN1 (0.60) ALOX5APFEN1
SCHEMBL15916285 0.83 FEN1 (0.72) ALOX5APFEN1
SCHEMBL21089481 0.82 ALOX5AP (0.56) ALOX5APFEN1
SCHEMBL20627398 0.80 FEN1 (0.50) ALOX5APFEN1
SCHEMBL20627305 0.77 FEN1 (0.65) ALOX5APFEN1
SCHEMBL20626956 0.74 ALOX5AP (0.70) ALOX5APFEN1
SCHEMBL20627532 0.73 FEN1 (0.61) ALOX5APFEN1
SCHEMBL20627407 0.72 FEN1 (0.57) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495359-A1 FLAP MODULATORS Janssen Pharmaceutica NV (BE) 2019-06-12 EP disclosed