Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BMI1 | P35226 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627758 | 0.83 | SMN1; SMN2 (0.42) | MAPK1HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL14222780 | 0.81 | MAPK1 (0.68) | MAPK1HTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7760076 | 0.78 | MAPK1 (0.79) | MAPK1HTTNPC1TSHRKDM4E | |
| SCHEMBL540947 | 0.78 | MAPK1 (1.00) | MAPK1HTTNPC1TSHRKDM4E | |
| SCHEMBL14004824 | 0.75 | MAPK1 (0.74) | MAPK1HTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL338236 | 0.75 | MAPK1 (0.74) | MAPK1HTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL22507416 | 0.75 | MAPK1 (0.74) | MAPK1HTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL19844108 | 0.75 | MAPK1 (0.80) | MAPK1HTTNPC1TSHRKDM4E | |
| SCHEMBL13495663 | 0.75 | MAPK1 (0.74) | MAPK1HTTNPC1TSHRKDM4E | |
| SCHEMBL9263231 | 0.75 | MAPK1 (0.74) | MAPK1HTTTSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |