Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891020 | 0.89 | MAPK1 (0.80) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL19844108 | 0.89 | MAPK1 (0.80) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL10041256 | 0.89 | MAPK1 (0.79) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL7760076 | 0.89 | MAPK1 (0.79) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL13030954 | 0.88 | HTT (0.79) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL1104833 | 0.87 | MAPK1 (0.77) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL9263231 | 0.85 | MAPK1 (0.74) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL22507416 | 0.85 | MAPK1 (0.74) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL13495663 | 0.85 | MAPK1 (0.74) | MAPK1HTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL15987567 | 0.85 | MAPK1 (0.74) | MAPK1HTTALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735586-B2 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI (FR) | 2014-05-27 | — | — | US | claimed |
| US-8188282-B2 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2012-05-29 | — | — | US | claimed |
| EP-2044033-B1 | A REGIOSELECTIVE PALLADIUM CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2012-02-08 | — | — | EP | claimed |
| EP-2173721-B1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI SA (FR) | 2011-12-28 | — | — | EP | claimed |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2010-10-14 | — | — | US | claimed |
| EP-2173721-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | Sanofi-Aventis (FR) | 2010-04-14 | — | — | EP | claimed |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | US | claimed |
| WO-2009000413-A1 | A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | claimed |
| EP-1878724-A1 | A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | sanofi-aventis (FR) | 2008-01-16 | — | — | EP | claimed |
| US-11873294-B2 | Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices | JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11873294-B2 | Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices | JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11818932-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-11-14 | — | — | US | disclosed |
| US-11812660-B2 | Organic compound, electroluminescent material and application thereof | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-11-07 | — | — | US | disclosed |
| US-11812660-B2 | Organic compound, electroluminescent material and application thereof | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-11-07 | — | — | US | disclosed |
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0138750-B1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BENZIMIDAZOLES | CIBA-GEIGY AG (CH) | 1987-09-09 | — | — | EP | disclosed |
| EP-0138750-A1 | Process for the production of substituted benzimidazoles | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4074046-A | REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11812660-B2 | Organic compound, electroluminescent material and application thereof | MRPS22, RPS3A, MRPS23 | MAPK1 1981/4885HTT 2936/4885ALDH1A1 2134/4885 |
| US-20100261909-A1 | Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles | AZI2, NISCH, UQCRB | MAPK1 3459/4885HTT 3225/4885ALDH1A1 97/4885 |
| US-20090203912-A1 | Regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles | DDT, NIT2, PADI1 | MAPK1 3566/4885HTT 2283/4885ALDH1A1 182/4885 |
| US-11873294-B2 | Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices | NLRP1, OCIAD2, OCIAD1 | MAPK1 3114/4885HTT 198/4885ALDH1A1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.