Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.45 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614863 | 0.92 | LPL (0.46) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL12423977 | 0.78 | LPL (0.41) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL23568130 | 0.78 | LPL (0.46) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL15615144 | 0.78 | LPL (0.46) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL24700307 | 0.78 | LPL (0.46) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL15614972 | 0.77 | LPL (0.46) | LPLLIPGF11CA1CA2 | |
| SCHEMBL24275638 | 0.77 | LPL (0.50) | LPLLIPGF11CA1CA2 | |
| SCHEMBL23294563 | 0.76 | LPL (0.47) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL16891264 | 0.76 | LPL (0.47) | LPLLIPGF11F2PRSS1 | |
| SCHEMBL29914599 | 0.76 | LPL (0.47) | LPLLIPGF11F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |