Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709510 | 0.92 | CA12 (0.34) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL20115513 | 0.88 | CES2 (0.36) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL27341113 | 0.88 | CES2 (0.33) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL23766685 | 0.87 | CA12 (0.37) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL22035307 | 0.86 | CES2 (0.32) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL24557245 | 0.84 | CA12 (0.35) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL22907293 | 0.83 | CES2 (0.31) | CA12CA1CA9CA2CES2 | |
| SCHEMBL21324002 | 0.83 | CES2 (0.31) | CA12CA1CA9CA2CES2 | |
| SCHEMBL20778802 | 0.82 | CA12 (0.33) | CA12CA1CA9CA2ZDHHC20 | |
| SCHEMBL25924428 | 0.79 | CA12 (0.36) | CA12CA1CA9CA2ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424524-A2 | CANCER RNA-VACCINE | CureVac AG (DE) | 2019-01-09 | — | — | EP | disclosed |