Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19755915 | 0.85 | POLB (0.37) | POLB | |
| SCHEMBL17896023 | 0.84 | POLB (0.37) | POLB | |
| SCHEMBL17896030 | 0.84 | POLB (0.39) | POLB | |
| SCHEMBL17009004 | 0.84 | POLB (0.37) | POLBDRD2DRD4DRD3GRM2 | |
| SCHEMBL17009008 | 0.82 | JAK2 (0.35) | POLB | |
| SCHEMBL20847439 | 0.82 | POLB (0.40) | POLBPIK3CAPRKAA2 | |
| SCHEMBL20847335 | 0.82 | POLB (0.36) | POLB | |
| SCHEMBL17901811 | 0.82 | POLB (0.36) | POLB | |
| SCHEMBL17623464 | 0.82 | CYP11B1 (0.34) | POLBCYP11B1CYP11B2DRD2DRD4 | |
| SCHEMBL14678088 | 0.81 | POLB (0.40) | POLBGRM2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |