Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24080716 | 0.89 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL20628629 | 0.88 | MAPK13 (0.34) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL20628349 | 0.79 | MAPK13 (0.36) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL20628351 | 0.78 | MAPK13 (0.37) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL18573463 | 0.76 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL12367621 | 0.76 | ALDH1A1 (0.60) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL20709641 | 0.75 | PDK2 (0.39) | KMT2AMEN1POLB | |
| SCHEMBL21159922 | 0.74 | BRAF (0.39) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL16858249 | 0.74 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1PTGS2MAPK1 | |
| SCHEMBL24370026 | 0.74 | ALDH1A1 (0.57) | MAPK13MAPK12MAPK11MAPK14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424907-A2 | CONNECTIONS AND ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |