Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628560 | 0.82 | BACE1 (0.63) | BACE1BACE2 | |
| SCHEMBL20628930 | 0.82 | BACE1 (0.72) | BACE1BACE2 | |
| SCHEMBL18493375 | 0.81 | BACE1 (0.72) | BACE1BACE2 | |
| SCHEMBL20628895 | 0.81 | BACE1 (0.75) | BACE1BACE2 | |
| SCHEMBL20628563 | 0.81 | BACE1 (0.66) | BACE1BACE2 | |
| SCHEMBL1173552 | 0.80 | BACE1 (0.68) | BACE1BACE2 | |
| SCHEMBL20628779 | 0.79 | BACE1 (0.70) | BACE1BACE2 | |
| SCHEMBL20628784 | 0.79 | BACE1 (0.61) | BACE1BACE2 | |
| SCHEMBL20628777 | 0.78 | BACE1 (0.74) | BACE1BACE2 | |
| SCHEMBL20628730 | 0.78 | BACE1 (0.69) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218362-B1 | 2-AMINO-3,5-DIFLUORO-3,6-DIMETHYL-6-PHENYL-3,4,5,6-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS FOR TREATING ALZHEIMER'S DISEASE | H LUNDBECK AS (DK) | 2019-01-09 | — | — | EP | disclosed |