Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | VDR | P11473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358868 | 0.82 | AAK1 (0.53) | AAK1HTTALDH1A1HPGDNPSR1 | |
| SCHEMBL15051963 | 0.80 | PTGDR2 (0.56) | HTTALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL9336808 | 0.80 | AAK1 (0.43) | AAK1HTTALDH1A1HPGDNPSR1 | |
| SCHEMBL257828 | 0.80 | HPGD (0.53) | ALDH1A1HPGDNPSR1POLBKDM4E | |
| SCHEMBL5009403 | 0.79 | AAK1 (0.45) | AAK1HTTALDH1A1HPGDNPSR1 | |
| SCHEMBL13475564 | 0.79 | VDR (0.39) | VDRHDAC3HDAC6 | |
| SCHEMBL28986747 | 0.78 | AAK1 (0.49) | AAK1ALDH1A1HPGD | |
| SCHEMBL15052191 | 0.78 | PTGDR2 (0.56) | ALDH1A1HPGDPOLBKDM4ETDP1 | |
| SCHEMBL21575178 | 0.77 | AAK1 (0.55) | AAK1HTTALDH1A1HPGDNPSR1 | |
| SCHEMBL4816249 | 0.77 | HPGD (0.57) | HTTALDH1A1HPGDNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |