Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 6/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 2/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | CHI3L1 | P36222 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686316 | 0.89 | CHIT1 (0.38) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL26438873 | 0.89 | CHIT1 (0.38) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL22903686 | 0.89 | CHIT1 (0.38) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL26438642 | 0.87 | ATM (0.38) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL22903581 | 0.86 | KCNH2 (0.47) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL28700089 | 0.86 | KCNH2 (0.47) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL26438837 | 0.86 | KCNH2 (0.47) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL28686358 | 0.86 | CHIT1 (0.37) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL26438893 | 0.86 | CHIT1 (0.37) | ATMCHIT1CHIAHTTSMN1; SMN2 | |
| SCHEMBL18607749 | 0.84 | CHIT1 (0.48) | ATMCHIT1CHIAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |