Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20754275 | 0.84 | NPSR1 (0.35) | NPSR1KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL23010185 | 0.79 | — | — | |
| SCHEMBL31723183 | 0.79 | NPSR1 (0.35) | NPSR1KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL23998022 | 0.79 | NPSR1 (0.35) | NPSR1KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL25612293 | 0.76 | NPSR1 (0.33) | NPSR1 | |
| SCHEMBL22281712 | 0.75 | NPSR1 (0.33) | NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL23030178 | 0.75 | NPSR1 (0.33) | NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL1355923 | 0.73 | NPSR1 (0.37) | NPSR1KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL16281538 | 0.73 | NPSR1 (0.37) | NPSR1KDM4EMEN1KMT2AEPHX1 | |
| SCHEMBL10254499 | 0.72 | SHBG (0.35) | NPSR1KDM4EEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797782-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | Janssen BioPharma, Inc. (US) | 2021-03-31 | — | — | EP | disclosed |
| EP-3424938-A1 | 4'-AZIDOALKYL-SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Alios Biopharma, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |