Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | BUB1 | O43683 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630367 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL20629820 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987537 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987535 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987481 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987394 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17963584 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17963607 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987317 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL17987347 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250569-B1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-01-09 | — | — | EP | disclosed |